Core faculty in the Center for Health Decision Science, with leadership from Drs. Prosser and Lieu with faculty seated at Department of Ambulatory Care and Prevention (DACP), are participating in a research agenda focused on interventions to improve the health and well-being of children. These studies include:

• a comprehensive review of sources of utility assessments in published studies analyzing children’s health interventions for cost-effectiveness.
  
  
• a CDC-sponsored study to assess and compare the preferences of adolescents with type 2 diabetes or pre-diabetes and their parents for states of health of those impacted by type 2 diabetes.
  
  
• an NIH-sponsored cluster-randomized controlled trial in 10 pediatric practices of a large multi-site group practice in eastern Massachusetts to evaluate the effectiveness and cost-effectiveness of an innovative, sustainable primary care intervention to prevent obesity among young children.
  
  
• an NIDCD- and NIAID-sponsored decision analysis using empirical cohort data and computer simulation to evaluate alternative strategies for otitis media vaccination and to identify how further investment in research can best influence future policy decisions.
  
  
• a CDC-sponsored series of economic studies to inform policy decisions about new vaccines and vaccine delivery programs for children.
  
  
• an evaluation of effects and costs of various influenza vaccination and treatment strategies in specific pediatric subgroups defined by age and risk status.
  
  
• an economic evaluation of newborn screening including programs for metabolic disorders.
  
  
• an  economic evaluation of hypertension screening among adolescents and young adults led by Dr. Wang, through collaborations with Dr. Gillman at DACP.